Frederic AUVRAY obtained a PhD in Microbiology from the University Paul Sabatier (Toulouse, France) in 1998. After a post-doc at the University of Cambridge (UK) as an EMBO fellow (1999-2001), he worked for 15 years as a research scientist at the Laboratory for Food Safety (Maisons-Alfort, France) which belongs to the French Agency for Food, Environmental and Occupational Health & Safety (Anses). During this period, his main interests included the detection and characterization of food-borne bacterial pathogens, such as Shigatoxin-producing E. coli (STEC) and Staphylococcus aureus. In September 2017, he joined the Veterinary School of Toulouse (ENVT) and more specifically the team “Pathogenesis and Commensalism of Enterobacteria” at the Digestive Health Research Institute (IRSD).
Escherichia coli belongs to the initial microflora colonizing the gut of humans and most warm-blooded animals. However, E. coli is also a highly versatile bacterial species with considerable pathogenic potential. E. coli is one of the most frequent causes of bacterial infections, including bacteremia, urinary tract infections, diarrhea, and other clinical life-threatening infections such as neonatal meningitis, hemorrhagic colitis and hemolytic uremic syndrome.
Frederic AUVRAY’s research focuses on molecular epidemiology and control of pathogenic and/or antimicrobial resistant E. coli strains and their transmission between animal reservoirs, the environment and humans.
Towards a reduction of the carriage of Enterohemorrhagic E. coli (EHEC) by domestic ruminants. Funded by Région Occitanie and DGER.
Control of Shiga-toxin producing E. coli (STEC) in French small ruminants dairy farms (CASTEC). Funded by FranceAgriMer.
Exploitation of antagonistic traits of E. coli Nissle 1917 to reduce carriage and spread of ESBL plasmids in intestinal enterobacteria (ECN-ReduceESBLEcoli). Funded by ANR.
Structure and function of the cellular target of the anti-Shiga toxin drug candidate Retro-2.1. (SMERSEC). Funded by ANR.
Créée en 1825, l’ENVT est la plus ancienne des grandes écoles Toulousaines. Sans discontinuer, elle a servi la société en formant le tiers, puis le quart des vétérinaires français et s’honore d’avoir hébergé de grands noms de la profession, cliniciens, chercheurs, enseignants, industriels et décideurs.